⌘K

/

/

Accelerating fibrosis and inflammation research through validated preclinical models and expert insights.

Research

モデル
薬剤
インサイト

Company

CROパートナー
Contact Us
Privacy Policy

© 2025 Fibrosis-Inflammation Lab. All rights reserved.

Privacy Policy Terms of Service

Zepbound (Tirzepatide) | 加速させる、線維化研究を

Home/Drugs/Zepbound

Zepbound

Tirzepatide

Phase 3

Sponsor: Eli Lilly

Indication: MASH / Obesity

Mechanism of Action

GLP-1/GIP Dual Agonist

Target: GLP-1Target: GIP

Clinical Information

Approval Year

Clinical Trials (ClinicalTrials.gov)

ACTIVE_NOT_RECRUITINGNCT06467604

CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

Org:University of California, Davis

COMPLETED

Relevant Publications (PubMed)

Efficacy of tirzepatide versus semaglutide in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial.

Neves JS, Leite AR, Vale C et al.

Diabetologia2025 Dec 19

Prospecting the use of tirzepatide in combating obesity in Pakistan.

Talha M, Nouman M

J Pak Med Assoc2025 Nov

GLP-1 Receptor Agonist-Associated Slimmer's Palsy: Implications for the Peripheral Nerve Surgeon.

Dhupati P, Kisiel SC, Unadkat K et al.

Ann Plast Surg2026 Jan 1

Acute Mesenteric Ischemia as a Severe Complication Associated With Tirzepatide: A Case Report and Safety Alert.

Validated Models

This drug has been validated in the following preclinical models:

NCT05260021

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both

Phase:PHASE3Org:Eli Lilly and Company

RECRUITINGNCT07128082

The Long COVID Treatment Trial

Phase:PHASE2Org:Scripps Translational Science Institute

NOT_YET_RECRUITINGNCT07247084

A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)

Phase:PHASE4Org:Eli Lilly and Company

ENROLLING_BY_INVITATIONNCT06451458

ECHO for Diabetes and Multiple Chronic Conditions Study

Phase:NAOrg:University of New Mexico

View all trials on ClinicalTrials.gov

Brooks S, Nafees S, Abdi K et al.

Cureus2025 Nov

Injectable drugs for weight management.

Yates N, South TL

Aust Prescr2025 Dec

View more on PubMed