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Pamrevlumab (pamrevlumab) | 加速させる、線維化研究を

Home/Drugs/Pamrevlumab

Pamrevlumab

pamrevlumab

Phase 3

Sponsor: FibroGen

Indication: IPF / Pancreatic Cancer

Mechanism of Action

Connective Tissue Growth Factor (CTGF) inhibitor

Target: CTGF

Clinical Information

Approval Year

Clinical Trials (ClinicalTrials.gov)

TERMINATEDNCT04419558

Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Phase:PHASE3Org:Kyntra Bio

COMPLETED

Relevant Publications (PubMed)

No recent publications found for pamrevlumab.

Validated Models

This drug has been validated in the following preclinical models:

NCT00102297

Study of the Safety of FG-3019 in Incipient Nephropathy Due to Type 1 or Type 2 Diabetes Mellitus

Phase:PHASE1Org:Kyntra Bio

COMPLETEDNCT02210559

A Study of Gemcitabine Plus Nab-paclitaxel With or Without FG-3019 in Participants With Locally Advanced, Unresectable Pancreatic Cancer

Phase:PHASE1, PHASE2Org:Kyntra Bio

COMPLETEDNCT05262309

An Open-label, Randomized, Parallel-arm Study Investigating the Efficacy and Safety of Intravenous Administration of Pamrevlumab Versus Standard of Care in Patients With COVID-19

Phase:PHASE2, PHASE3Org:Fondazione Policlinico Universitario Agostino Gemelli IRCCS

WITHDRAWNNCT02851381

Compassionate Single Subject Use of FG-3019 (FibroGen) in Locally Advanced, Unresectable Pancreatic Cancer

Phase:NAOrg:Jonsson Comprehensive Cancer Center

View all trials on ClinicalTrials.gov