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STZ-Induced Diabetic Nephropathy | Accelerate Your Fibrosis Research

Home/Models/STZ-Induced Diabetic Nephropathy

STZ-Induced Diabetic Nephropathy

chemicaldiabeteskidney

Species

Mouse

Duration

Protocol ID

M-cG9zdDoyMjk=

Model Overview

Models diabetic kidney disease using streptozotocin-induced diabetes.

Methodology

Key Endpoints

Albuminuria
Glomerular hypertrophy
Mesangial expansion

Relevant Publications

MiR-10a-5p aggravates podocyte injury in diabetic nephropathy by inhibiting E2f7-mediated autophagy.

Tong W, Liu T

Diabet Med2026 Mar 12

Ethnopharmacological relevance and anti-inflammatory mechanisms of Lycopi Herba in diabetic nephropathy: Integrated chemical profiling and pharmacological evaluation.

Chen LZ, Yang S, Ren DM et al.

J Ethnopharmacol2026 Mar 7

Potential Involvement of PI3K/AKT Signaling Pathway in the Protective Effects of Rhinacanthus nasutus Against Diabetic Nephropathy-Induced Oxidative Stress.

Liu J, Lin Y, Yi X et al.

Antioxidants (Basel)2026 Feb 14

Licochalcone B suppresses oxidative stress and apoptosis accompanied by upregulating Nrf2/HO-1 pathway to ameliorate diabetic nephropathy in mice.

Luo S, Lan Y, Zhang R et al.

Front Pharmacol2025

Calebin A mitigates oxidative stress and inflammation in diabetic nephropathy via Nrf2/HO-1 and NF-κB signaling pathways.

Vatanparast RG, Aliyari M, Yazdi MP et al.

J Diabetes Investig2026 Feb 19

View more on PubMed