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DSS-Induced Colitis | Accelerate Your Fibrosis Research

Home/Models/DSS-Induced Colitis

DSS-Induced Colitis

chemicalgutinflammation

Species

Mouse

Duration

Protocol ID

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Model Overview

Widely used model of ulcerative colitis.

Methodology

Key Endpoints

Disease Activity Index (DAI)
Colon length
Histology score

Relevant Publications

OTOP2 Proton Channel Couples Luminal pH Sensing to Intestinal Immune Homeostasis.

Yan W, Wang Y, Zhao H et al.

J Biol Chem2026 May 6

Eupalinolide B alleviates ulcerative colitis by targeting HMGB1 through modulation of the HMGB1/TLR4/MyD88/NF-κB signaling pathway.

Luo W, Zhuang Y, Shen S et al.

Phytomedicine2026 Apr 25

Ovotransferrin Alleviates Ulcerative Colitis by Modulating Ligilactobacillus murinus-Mediated Bile Acid Metabolism via the Ptgs2/JAK-STAT Signaling Axis.

Zheng D, Xin X, Ouyang H et al.

J Agric Food Chem2026 May 7

n-3 Polyunsaturated Fatty Acids Improve DSS-Induced Acute Colitis in Mice via Intestinal Barrier Fortification and Gut Microbiome Modulation.

Hu X, Chen J, Zhou Y et al.

Dig Dis Sci2026 May 7

Selenized Probiotic L. brevis 23017 Alleviates Colitis by Modulating the Nrf2-GPX4 Axis to Inhibit Ferroptosis.

Zhuang Y, Liu Q, Shi F et al.

Biol Trace Elem Res2026 May 7

View more on PubMed