Tanzisertib

Inhibition of the MAPK/c-Jun-EGR1 Pathway Decreases Photoreceptor Cell Death in the rd1 Mouse Model for Inherited Retinal Degeneration.

Dong Y, Xu W, Li Y et al.

Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001.

Nagy MA, Hilgraf R, Mortensen DS et al.

Metabolism and disposition of a potent and selective JNK inhibitor [14C]tanzisertib following oral administration to rats, dogs and humans.

Atsriku C, Hoffmann M, Ye Y et al.

In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism.