Partner with an independent fibrosis & inflammation knowledge hub
We cover preclinical models, biomarkers, and drug pipelines with full editorial independence. If you'd like to sponsor, collaborate, or reach our editorial team, start here.
Why this page exists
Fibrosis-Inflammation Lab is an independent publication. This page exists so that researchers, CRO business teams, reagent/instrument/SaaS vendors, and editorial collaborators can reach us through the right channel.
Our readership reaches us through organic search on preclinical models, biomarkers, and fibrosis/inflammation drug pipelines. If you're considering a sponsorship or partnership, this is the audience you'd be reaching.
Because our CRO-ranking articles are designed to be useful even when no one is paying us, we are deliberately slow to open direct sales conversations. If you represent a CRO and are looking for outbound leads, please note our current stance below.
Why fibrosis-specific selection matters
Preclinical fibrosis programs face challenges that general-purpose CROs are rarely structured to address. The differences below reflect the practical selection criteria research leaders apply when comparing fibrosis-specialist providers against generalist contractors.
Disease coverage & model validation
Fibrosis-specialist programs span six organ systems (liver, lung, kidney, heart, skin, GI) with LITMUS-ranked or consortium-validated models, while generalist CROs typically support 1–2 disease areas with single published models.
Example: GAN DIO-MASH (LITMUS top-tier), bleomycin IPF, UUO renal — all maintained as standing colonies under one roof.
Fibrosis quantification stack
Specialist providers run a multi-layer quantification stack — Sirius Red %Area, hydroxyproline HPLC, α-SMA qPCR, and AI digital pathology — in parallel. Generalist CROs typically deliver only ordinal pathologist scoring (0–4).
Example: PharmaNest FibroNest™ AI + biochemical hydroxyproline + IHC α-SMA, all reported in a single dataset.
Study duration & cost transparency
MASH and chronic kidney protocols often run 20+ weeks, where housing cost can reach 30–40% of the total budget. Best-practice quotes flag this upfront and ship interim hypothesis reports; generalist quotes often hide it under per-test pricing.
Example: 24-week GAN-Diet study with weeks 8 / 16 interim reports and an itemized housing line.
Regulatory & data integrity (ALCOA+)
Fibrosis-specialist providers operate GLP-aligned facilities with IND-enabling track records, ELN audit trails, and full raw-data + image-file delivery. Generalist contractors may deliver summary tables only, with limited regulatory traceability.
Example: ELN-backed audit trail, full TIFF stack delivery, GLP-grade SEND datasets on request.
Scientific partnership
Best-practice fibrosis programs are led by a PhD study director with bi-weekly scientific calls and root-cause analysis whenever a study underperforms. Generalist contractors typically operate transactionally — results in, report out.
Example: Sponsor-side decision such as "continue at higher dose" vs "pivot to companion biomarker" — informed by partner-led RCA.
Editorial & sponsorship policy
- Sponsorship does not guarantee editorial coverage, ranking changes, or favorable evaluation. Editorial decisions are made independently of any commercial arrangement.
- Editorial content is built exclusively on public sources: peer-reviewed publications, conference abstracts, publicly disclosed clinical trial data, and regulatory materials.
- No paid rankings. CRO mentions in our comparison articles reflect editorial judgment, not commercial arrangements.
- Sponsored placements (if introduced) will be clearly disclosed on the affected page with the label "Sponsored" and a named sponsor.
- Corrections and update requests are welcome — use the Editorial track of the form below.
Get in touch
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Available disease models
For organizations considering outreach, here are the disease areas already covered by our models directory. You can browse each category to get a sense of the topical depth before reaching out.
Hepatic (Liver)
AMLN, GAN, STAM, CCl4 and related NASH/MASH and fibrosis models.
Browse models →Pulmonary (Lung)
Bleomycin-induced pulmonary fibrosis, silica, and IPF-adjacent models.
Browse models →Renal (Kidney)
UUO, adenine-induced CKD, and related nephropathy models.
Browse models →Cardiac (Heart)
Pressure overload, Ang II infusion, and cardiomyopathy models.
Browse models →Dermal (Skin)
Bleomycin-induced, TSK, and scleroderma-adjacent models.
Browse models →Gastrointestinal
DSS, TNBS, and other colitis / IBD models.
Browse models →None of these fit?
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